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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T16333 | NKY80 | Adenylyl cyclase type V Inhibitor | Adenylyl cyclase |
NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues. NKY80 is a non-competitive inhibitor of adenylyl cyclase type V isoform (IC50s: 8.3 µM, 132 µM, and 1.7 mM for type V, III and II, respe... | |||
T10066 | 2',5'-Dideoxyadenosine | Adenylyl cyclase , Adrenergic Receptor , AChR | |
2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM). | |||
T15658 | KH7 | cAMP , AChR | |
KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific. It has IC50s of 3-10 μM toward both recombinant purified human sACt protein and heterologously expressed sACt in cellular assays. KH7 is also a cAMP inhibito... | |||
T16938 | ST034307 | Adenylyl cyclase | |
ST034307 is an effective and selective inhibitor of adenylyl cyclase 1 (IC50: 2.3 μM). | |||
T60003 | AC1-IN-1 | Adenylyl cyclase | |
AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM). | |||
T0322 | Fipexide | Dopamine Receptor , AChR | |
Fipexide (Attentil, Vigilor), a psychoactive drug of the piperazine chemical class, was developed in Italy in 1983. It was served as a nootropic drug in France and Italy, mainly for the therapy of senile dementia, but is... | |||
T16275 | NB001 | HTS 09836 | Adenylyl cyclase |
NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain. | |||
T83169 | Adenylyl cyclase-IN-1 | ||
Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1]. | |||
T2939 | Forskolin | Coleonol,Colforsin | FXR , Adenylyl cyclase , AChR , Autophagy |
Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the... | |||
T26869 | BMS-986122 | BMS 986122 | Opioid Receptor |
BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1 human osteosarcoma cells expressing μ-opioid receptors (EC5... | |||
T8702 | SKF-83566 | Dopamine Receptor , 5-HT Receptor , AChR | |
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 nM | |||
T63893 | Adenylyl cyclase type 2 agonist-1 | ||
Adenylyl cyclase type 2 agonist-1 is a potent agonist of adenylyl cyclase type 2 (AC2) (EC50: 90 nM). It is a potential lead compound in the fight against respiratory diseases. | |||
T2172 | SQ22536 | 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine,SQ 22536 | AChR |
SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) , the adenosine analogue 9-(Tetrahydro-2-furyl)adenine, inhibited adenylate cyclase activity of crude membrane preparations from catfish (Ictalurus melas) and rat isola... | |||
T11918 | Lysipressin | Lysine vasopressin,[Lys8]-Vasopressin | Others |
Lysipressin ([Lys8]-Vasopressin), Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families. | |||
T15787 | LRE1 | Adenylyl cyclase | |
LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor. | |||
T7813 | α-MSH | MSH, amide,CZEN-002,α-Melanocyte-Stimulating Hormone (MSH), amide | Melanocortin Receptor , Adenylyl cyclase |
α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase. | |||
T8959 | OS-3-106 | Dopamine Receptor | |
OS-3-106 is a novel arylamide phenylpiperazines, as partial agonists at the D3R in the adenylyl cyclase inhibition assay. | |||
T64355 | TDI-10229 | cAMP | |
TDI-10229 is a potent and orally available inhibitor of soluble adenylyl cyclase (sAC, ADCY10). TDI-10229 displays nanomolar inhibition of sAC in both biochemical and cellular assays (IC50= 195 nM). TDI-10229 exhibits mo... | |||
T22615 | BPIPP | Others | |
guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor | |||
T23863 | CB-6673567 | CB 6673567 | |
CB-6673567 is a selective inhibitor of adenylyl cyclase. |